Research within the division includes laboratory- and clinic-based studies related to our field.
We invite you to connect with our current clinical trials or learn more about our faculty members’ research below.
Applying minimally invasive endoluminal technology for the treatment of vascular disease.
Mark K. Eskandari, MD, is the James S. T. Yao, MD, PhD, Professor of Education in Vascular Surgery and serves as the chief of the Division of Vascular Surgery. He has adjunct appointments in the Departments of Radiology and Cardiology and is on staff at Northwestern Memorial Hospital, Northwestern Lake Forest Hospital, and Rehabilitation Institute of Chicago. As a vascular and endovascular surgeon, his primary research interests are in the application of minimally invasive endoluminal technology for the treatment of vascular disease. The focus of his clinical research has included therapies for carotid artery disease, aortic aneurysms, and aortic dissections. Dr. Eskandari has been actively involved in numerous clinical research trials assessing the results of carotid artery stenting as compared to traditional carotid artery surgery (endarterectomy) for stroke prevention. His work in this endeavor has been extensively published in the medical literature and he is considered a national expert in this area. Similarly, his experience in endovascular treatment of abdominal and thoracic aortic aneurysm as well as thoracic aortic dissections is exemplified by several national and international presentations, papers, and training courses given under his guidance.
Investigating the effect of chronic kidney disease on the vascular wound healing response.
Dr. Karen J. Ho joined the Division of Vascular Surgery as an Assistant Professor of Vascular Surgery in September 2013. Dr. Ho is a graduate of Yale College and Harvard Medical School. She completed a residency in general surgery as well as a fellowship in vascular and endovascular surgery at Brigham and Women’s Hospital. Dr. Ho has received numerous awards for research and teaching. She has published and presented on subjects including carotid and peripheral vascular disease. Dr. Ho is a surgeon-scientist with interests that encompass clinical vascular surgery and basic science research. Dr. Ho’s current research interests are primarily focused on chronic kidney disease, wound healing, and peripheral vascular disease. She is specifically interested in the effect of chronic kidney disease on the vascular wound healing response.
Evaluating new therapies for treatment of arterial vascular disease.
Dr. Andrew W. Hoel has specific training, interest and expertise in the endovascular treatment of complex aortic aneurysms. This is an outgrowth of his vascular surgical training at Dartmouth-Hitchcock Medical Center, which specifically emphasized advanced endovascular techniques. In addition, he is interested in studying clinical and outcomes research in vascular surgery. He is active in several committees in regional and national vascular surgical outcomes groups and involved in multiple clinical trials evaluating new therapies for treatment of arterial vascular disease.
Focusing on nitric oxide vascular biology.
Melina R. Kibbe, MD, is a Professor of Surgery at the Northwestern University Feinberg School of Medicine, Division of Vascular Surgery, and is on staff at Northwestern Memorial Hospital and Jesse Brown VA Medical Center, where she serves as director of the Vascular Laboratory and co-chief of the Division of Vascular Surgery. Dr. Kibbe's research interests focus on nitric oxide vascular biology. Specifically, she is studying how nitric oxide inhibits vascular smooth muscle cell proliferation by focusing on the role of nitric oxide in regulating the cell cycle, the ubiquitin-proteasome pathway, and apoptosis. She is also developing and evaluating nitric oxide-based pharmacological and bioengineering approaches to inhibit neointimal hyperplasia following vascular interventions, including bypass grafting and peripheral angioplasty/stenting. Her hope is to have a positive effect on patency rates of these procedures, thereby effecting millions of patients that undergo coronary artery or peripheral artery revascularization procedures. In 2010, she received the Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States Government on young professionals in the early stages of their independent research careers.
Learn more via the Kibbe Lab website.
Studying endothelial seeding and the pathogenesis of abdominal aortic aneurysms.
William H. Pearce, MD, Violet R. and Charles A. Baldwin Professor of Vascular Surgery, is a nationally prominent vascular surgeon. He is on staff at Northwestern Memorial Hospital, Jesse Brown VA Medical Center, Northwestern Lake Forest Hospital, Ann & Robert H. Lurie Children's Hospital of Chicago, and Rehabilitation Institute of Chicago. Dr. Pearce has been actively involved in basic science research, studying endothelial seeding and the pathogenesis of abdominal aortic aneurysms (AAA). In 1992, he received the NIH Academic Award in Systemic and Pulmonary Vascular Disease as one of a few surgeons recognized for their contributions to a better understanding of vascular diseases and was co-investigator with Rex Chisholm, PhD, on the pathogenesis of AAA grant. He served as a member of the Surgery and Bioengineering (SBE) NIH Study Section (1998-2001). Dr. Pearce has wide-ranging investigative interests and currently is co-investigator on several grants establishing a center for vascular research as well as co-PI on an R-12 Vascular Medicine Training Grant. In addition, he serves as program director of an NIH-funded (T-32) program designed to train vascular surgeon-scientists (Vascular Surgery Scientist Training Program).
Studying minimally-invasive treatment of aneurysms and lower extremity occlusive disease.
Heron E. Rodriguez, MD, is an Associate Professor of Surgery at Northwestern University's Feinberg School of Medicine, Division of Vascular Surgery, and co-director of the Limb Preservation Clinic. He is on staff at Northwestern Memorial Hospital, Northwestern Lake Forest Hospital, and Rehabilitation Institute of Chicago. His clinical activities focus on arterial and venous surgery and percutaneous interventions. Areas of special interest include lower extremity revascularization and arterial aneurysms. He has active research interests in minimally invasive treatment of aneurysms and lower extremity occlusive disease.